Is pulsed dose rate more damaging to spinal cord of rats than continuous low dose rate?
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چکیده
منابع مشابه
Is pulsed dose rate more damaging to spinal cord of rats than continuous low dose rate?
BACKGROUND AND PURPOSE Theoretical calculations suggest that pulsed dose-rate irradiation (PDR) should have approximately the same effectiveness as continuous low dose-rate (CLDR) when the same total dose is given in the same overall time, unless large doses per pulse (> 2 Gy) are used and/or non-exponential or very short half-times of repair (< 0.5 h) are present in the irradiated tissues. How...
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The capability of the TrueBeam treatment system to deliver step and shoot IMRT plans at low dose rates was evaluated. Beam characteristics during low dose rates (5 to 100 MU/min) were evaluated for consistency using a planar ion chamber array. MU constancy, linearity, and beam profile symmetry were all found to be equivalent within 0.5%. The response of the Scandi Dos Delta 4 system was also ev...
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BACKGROUND Most tumor cell lines exhibited low-dose hyperradiosensitivity (LDHRS) to radiation doses lower than 0.3 Gy. Pulsed low-dose rate radiotherapy (PLDR) took advantage of LDHRS and maximized the tumor control process. In this study, we retrospectively analyzed patients receiving PLDR for refractory malignancies. PATIENTS AND METHODS In total, 22 patients were included in our study: 9 ...
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PURPOSE PURPOSE To present our experience with pulsed dose rate brachytherapy (PDR BT) of lip cancer. MATERIAL AND METHODS The study group included 32 T1-4N0M0 lip cancer patients with a median age of 71 years (ranged 41-87 years), treated with interstitial PDR BT to the planned total dose of 60-70 Gy; 1 Gy/pulse, pulses repeated every hour a day. There were 26 untreated patients, and six ...
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Pulsed dose rate (PDR-BT) treatment is a brachytherapy modality that combines physical advantages of high-dose-rate (HDR-BT) technology (isodose optimization, radiation safety) with the radiobiological advantages of low-dose-rate (LDR-BT) brachytherapy. Pulsed brachytherapy consists of using stronger radiation source than for LDR-BT and producing series of short exposures of 10 to 30 minutes in...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 1997
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(97)00172-2